Journal Club

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Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo

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Check out this paper, provided by visiting student scholar Jie Li, on how pericytes act differently in vitro versus in vivo, and how they relate to MSC-like behavior. Read the PaperRead the rest

PDGFR-β (+) ASCs From SVF Are Good Sources of Pericytes and Have Multilineage Potential

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This paper, from Seoul, Korea, examines the isolation and enrichment of PDGFR-β (+) ASCs and how they interact with the vasculature and exhibit chondrogenic, osteogenic, and adipogenic differentiation. They found that, even in ischemic patients, the SVF holds a … Read the rest

Exogenous ASCs Improve Wound Healing in Ulcers

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This paper describes how exogenously delivered ASCs to an induced rat ulcer improved wound healing, vascularization, and re-epithelialization. Additionally, ASCs accelerating the rate of wound healing. Read the paper to get all the details.… Read the rest

Adipose-Derived Stem Cells for Regenerative Medicine

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This fantastic review by one of LaCell’s co-founder’s, Dr. Jeffrey Gimble, takes us through where to get adult stem cells, how they are currently being isolated, methods to characterize the cells and some fascinating applications of stem cell technology. Check … Read the rest

Role of ASCs in wound healing and skin repair

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Did you know that over 2.5 million patients require treatment for pressure ulcer’s every year in the United States? Patients suffer a significant decrease in quality of life from these painful ulcer’s. This also represents an approximately $11 billion burden … Read the rest

Screening hASCs for therapeutic relevancy

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A group at Stanford University recently developed a high-throughput screening technique to isolate individual human adipose-derived stem/stromal cells (hASCs) for targeted use in specific therapeutics. ASC subpopulations vary depending on the source, and to maximize the regenerative potential of ASCs, … Read the rest

Interesting Journal Articles

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We will be begin weekly postings of interesting journal articles and information on breakthroughs in treatments using adipose and bone marrow derived stem/stromal cells (ASC and BMSC).

To begin, an extremely informative review by co-founder Jeffrey M Gimble, PhD on … Read the rest